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lafountainDr. James R. LaFountain

Professor
Office: Cooke 657
Office Hours: Tue, Thu 8:00 – 9:00am
Tel: (716) 645-4965
E-mail: jrl@buffalo.edu

Ph.D. The State University of New York, Albany

Further research info

Research Summary

My research addresses questions about the mechanism underlying the segregation of chromosomes during meiosis. Current experiments entail use of laser microsurgery to release kinetochores from tension, and this is followed by studying the relationship between movement of released kinetochores and the dynamic flux of microtubules attached to them. See recent publications for details.

Recent Publications

  • LaFountain, J.R., Jr., and Oldenbourg, R. 2014. Kinetochore-driven outgrowth of microtubules is a central contributor to kinetochore fiber maturation in crane-fly spermatocytes. Molecular Biology of the Cell 25: 1437-1445.
  • LaFountain, J.R., Jr., Cohan, C.S. and Oldenbourg, R. 2011. Functional states of kinetochores revealed by laser microsurgery and fluorescent speckle microscopy. Molecular Biology of the Cell 22: 4801-4808
  • LaFountain, J.R., Jr., Cohan, C.S. and Oldenbourg, R. 2012. Pac-man motility of kinetochores unleashed by laser microsurgery. Molecular Biology of the Cell 23: 3133-3142.